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HassP150 multi-channel high-throughput protein purification system

HassP150 multi-channel high-throughput protein purification system

Introduction:

    • Multi channel: A single computer controls multiple instruments, which can be parallel or serial
    • One computers: control up to 16 units
    • Flow rate range: 0~150mL/min customizable
    • Pressure resistance: maximum 40Mpa (5600psi)
    • Wavelength range: (190-500nm), customizable (190-850nm)
    • Detection wavelength: Simultaneous detection of three wavelengths, customizable (6, 10, 15, full wavelength)
    • Absorption range: ± 6AU
    • Interface: Ethernet communication

Scope of application

Universal pilot grade protein purification system, with adjustable modules. Research and production of biological proteins, antibodies, vaccines, and other applications ranging from laboratory to industrial levels. Mainly serving major biotech companies and CRO/CDMO enterprises, providing them with comprehensive solutions for research and development as well as production. This product is mainly used in scenarios of fast and parallel production, such as the same purification process. Up to 40 1L samples can be processed overnight in 8 parallel machines, greatly improving production efficiency.

 

Message inquiry Online customer service contact

Item Parameter Notes
Appearance (W × D × H) – [mm]: 284 × 380 × 390
System Pump Flow Rate Range: 0–150 mL/min
Maximum Pressure: 10 MPa / 1400 psi
Flow Repeatability: 1–150 mL/min, <3 MPa, 0.8–2 cP
Flow Accuracy: ±1%
Flow Precision: RSD <0.5%
Gradient Accuracy: ±0.6%
Interface: Ethernet communication
Pressure Sensor: 0–20 MPa, accuracy ±0.025 MPa
Cleaning: Automatic flushing
Standard single pump: 150 mL/min
Optional external Pump B
Supports constant pressure mode and pressure control mode
Mixer Dynamic mixer: standard 1.4 mL, optional 5 mL or 10 mL Standard 1.4 mL
UV Detector Single-wavelength LED light source, Abs: ±6 AU Single wavelength 280 nm
Optional: 190–500 nm, 3 wavelengths
Optional: 190–850 nm, 3 wavelengths
Conductivity / Temperature Monitor Conductivity: 0–999 mS/cm
Resolution: 0.01 mS/cm
Accuracy: ±1.0% (0–300 mS/cm)
Automatic temperature compensation
Standard
pH Valve pH range: 0–14
Resolution: 0.01
Accuracy: ±0.05
7-position, 5-port valve
pH electrode and restrictor can be online or bypassed
1: Restrictor → pH
2: Restrictor
3: pH
4: Bypass
5: Restrictor
Communication Interface TCP/IP, 100 Mbps Ethernet Standard
Accessory Kit Tubing, fittings and accessories Standard
Chromatography Workstation Chinese / English user interface, including instrument control, method editing,
data processing, report printing, user and result database, encrypted database
management, peak integration, quantitative analysis, audit trail, scouting,
channel scouting, method programming and 8-channel parallel operation.
Standard
Pump A Inlet Valve Pump A inlet valve, maximum pressure 10 MPa, optional 3 / 7 / 13 channels 12 channels + 1 common port high-pressure rotary valve (13 channels)
Pump B Inlet Valve Pump B inlet valve, maximum pressure 10 MPa, optional 3 / 7 / 13 channels None
Sample Pump Inlet Valve Sample pump inlet valve, maximum pressure 10 MPa, optional 3 / 7 / 13 channels 6 channels + 1 common port high-pressure rotary valve (7 channels)
Air Sensor, Inlet A External ultrasonic air sensor Standard, optional built-in ultrasonic sensor
Air Sensor, Inlet B External ultrasonic air sensor None
Air Sensor, Sample Pump Inlet External ultrasonic air sensor None
Injection Valve 8-position, 6-port high-pressure rotary valve, pressure rating 30 MPa 1: Manual Load
2: Inject
3: System Pump Waste
4: Sample Pump Load
5: Direct Inject
6: Sample Pump Waste
V Valve 1: 1–2
2: 3–4
3: 1–3
4: 2–4
Pressure rating: 30 MPa
None
Column Valve Configurable, pressure rating 30 MPa
Optional: 2-column valve / 2-column valve with reverse flow / 6-column valve with reverse flow
6-column valve, 5 column flow paths, 1 bypass line
Column Delta Pressure Module Pre-column pressure, post-column pressure and delta pressure Standard
Outlet Valve Maximum pressure 10 MPa, optional 3 / 7 / 13 channels 12 channels + 1 common port high-pressure rotary valve (13 channels)
Back Pressure Valve / Flow Restrictor HY-FR802 Standard system back pressure: 0.2 MPa
Fraction Collector 1. Frac100A: Open type, compatible with standard XY100 tubes
2. Frac100B: Enclosed cabinet, 6 racks, compatible with 50 mL and 15 mL tubes, automatic rack recognition
3. Frac100B-1: Enclosed cabinet, 6 racks, compatible with 50 mL tubes, 15 mL tubes, 24-well plates, 48-well plates and 96-well plates, automatic rack recognition
4. Frac100B-2: Enclosed cabinet, 6 racks, compatible with 50 mL tubes, 15 mL tubes, 24-well plates, 48-well plates and 96-well plates, with UV sterilization and temperature / humidity sensor, automatic rack recognition
5. Frac100C: Enclosed cabinet, 6 racks, compatible with 50 mL tubes, 15 mL tubes, 24-well plates, 48-well plates and 96-well plates, with UV sterilization, temperature / humidity sensor and TE cooling, automatic rack recognition
None
Sample Pump Flow Rate Range: 0–150 mL/min
Maximum Pressure: 10 MPa / 1400 psi
Flow Repeatability: 1–150 mL/min, <3 MPa, 0.8–2 cP
Flow Accuracy: ±1%
Flow Precision: RSD <0.5%
Gradient Accuracy: ±0.6%
Interface: Ethernet communication
Pressure Sensor: 0–20 MPa, accuracy ±0.025 MPa
Cleaning: Automatic flushing
None
SDK & Communication Protocol Optimized proprietary command set. Tested development libraries are provided,
including .NET libraries, C/C++ DLLs and sample source code.
Suitable for secondary development.
Human-Machine Interface Windows 7 / Windows 10 / Windows 11 Configuration: Intel i3 processor or above, memory ≥8 GB, storage ≥256 GB, display resolution 1920 × 1080
Power Supply 110–220 VAC, ±5%
Operating Temperature -10°C to 40°C, non-condensing
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